Drug Absorption Mechanisms — primary?
Passive diffusion is the main mechanism.
Factors affecting absorption — key?
pH, surface area, blood flow, formulation.
Volume of Distribution — meaning?
Theoretical volume relating drug amount to plasma concentration.
Passive Diffusion — mechanism?
Drugs cross membranes down concentration gradient, no energy.
Facilitated Diffusion — difference?
Carrier-mediated, no energy, specific to drugs.
Active Transport — process?
Energy-dependent, moves against gradient via carriers.
Bioavailability (F) — definition?
Proportion of dose reaching circulation unchanged.
Ionization & pH — impact?
Affects drug lipophilicity and absorption.
Factors influencing absorption
Surface area, blood flow, formulation, pH.
Drug absorption mechanisms — importance?
Determine onset, efficiency, and route effectiveness.
Answer 10 questions on Fundamentals of Drug Absorption and Metabolism.
1. Which of the following best defines 'drug absorption mechanisms' in pharmacology?
2. According to the course content on factors affecting absorption, how does pH influence the absorption of weak acids and weak bases?
Go over the full study guide for Fundamentals of Drug Absorption and Metabolism.
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