GLUTs — function?
Facilitate glucose transport across membranes.
Hexokinase vs Glucokinase — difference?
Hexokinase has low Km, feedback-inhibited; glucokinase has high Km, not inhibited.
PFK1 — regulation?
Allosterically regulated by ATP, ADP, citrate, and F2,6P.
GLUTs — transport mechanism?
Facilitated diffusion without ATP.
GLUT1 — tissue?
High in brain and erythrocytes.
GLUT2 — role?
Glucose sensor in liver and pancreas.
Insulin-regulated GLUT?
GLUT4 translocates in muscle and adipose.
Km — significance?
Indicates transporter affinity for glucose.
Hexokinase — regulation?
Inhibited by G6P, high affinity for glucose.
Glucokinase — characteristic?
High Km, no feedback inhibition, in liver.
Answer 10 questions on Glucose Metabolism Mastery.
1. What is the primary role of glucose phosphorylation enzymes in metabolism?
2. What are Glucose Transporters (GLUTs) primarily classified as?
Go over the full study guide for Glucose Metabolism Mastery.
Read the study guide →Upload your class notes and Revizly writes your flashcards in about a minute.
Flashcard maker