Pancreatic islets — cell types?
β-cells produce insulin; α-cells produce glucagon.
Proinsulin — domains?
α-chain, β-chain, C-peptide.
Islets of Langerhans
Small pancreatic clusters secreting hormones
Insulin primary producer
Produced by β-cells
Glucagon producer
Produced by α-cells
Proinsulin parts
β-chain, α-chain, C-peptide
Insulin release pattern
Biphasic: quick and sustained
Insulin actions
Lowers blood glucose and promotes storage
Blood glucose regulation
Insulin decreases, glucagon increases blood sugar
Answer 11 questions on Hormonal Regulation of Blood Glucose.
1. Which pancreatic islet cell type produces and secretes insulin?
2. What is the main endocrine role of the islets of Langerhans?
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