Immunosuppressant Classes
Drugs that inhibit immune activity for transplantation or autoimmune diseases.
Chemotherapy Mechanisms
Agents disrupt DNA, mitosis, or specific pathways in cancer cells.
Immune System Components
Includes innate and adaptive immunity with lymphocytes, antigens, cytokines.
Immunosuppressants — definition?
Drugs that inhibit immune activity.
Calcineurin inhibitors — role?
Block T-cell activation by inhibiting IL-2.
Antimetabolites — mechanism?
Interfere with nucleotide synthesis.
mTOR inhibitors — effect?
Reduce T-cell proliferation and angiogenesis.
Chemotherapy — primary mechanism?
Damages DNA to kill dividing cells.
Alkylating agents — action?
Cause DNA cross-linking and strand breaks.
Antimetabolites — example?
Methotrexate.
Answer 9 questions on Immunosuppressants and Chemotherapy Strategies.
1. What are immunosuppressant classes?
2. Which of the following chemotherapy agents works primarily by adding alkyl groups to DNA, causing cross-linking and strand breaks?
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