Clonidine: Alpha2 “center” → calmer sympathetic output; Parasympatholytics → dry/wide pupils, but bladder sphincter doesn’t relax.
1. Which drug is a centrally acting alpha2-adrenergic agonist used for hypertension and opioid withdrawal treatment?
2. What is the expected effect of beta-adrenergic receptor stimulation on the uterus?
3. Which antipsychotic is least likely among the listed atypical agents to cause extrapyramidal symptoms?
Clonidine — role?
Centrally acting alpha2-agonist for hypertension.
Parasympatholytic drugs — effect?
Antagonize parasympathetic signaling, reduce secretions.
Beta-adrenergic receptors — effect?
Stimulation relaxes the uterus.
Antidopaminergic neuroleptics — adverse effect?
Extrapyramidal symptoms like pseudo-parkinsonism.
Pseudo-parkinsonian syndrome — cause?
Dopamine-blocking antipsychotics like haloperidol.
Benzodiazepines — primary action?
Enhance GABA neurotransmission, produce anxiolysis.
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