1. What does Flavivirus classification refer to?
2. Which mosquito species are primarily responsible for transmitting flaviviruses such as Dengue and Zika?
3. What is the primary purpose of flavivirus replication occurring within ER-derived vesicles in the host cell cytoplasm?
Flaviviruses — classification?
Positive-sense ssRNA viruses in Flaviviridae.
Flavivirus genome — type?
Non-segmented, single polyprotein RNA.
Flavivirus replication — location?
Cytoplasm within ER-derived vesicles.
DENV vectors — primary?
Aedes aegypti and albopictus mosquitoes.
Zika manifestations — congenital?
Microcephaly and congenital Zika syndrome.
Flavivirus entry — mechanism?
Receptor-mediated endocytosis and fusion.
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