ADR — definition?
Unintended, harmful response at normal doses.
ADR & mechanism — role?
Results from pharmacodynamic or pharmacokinetic factors.
Side effects — properties?
Related to drug's pharmacology; may be beneficial or neutral.
ADR — definition?
Unintended, noxious response to drug at normal doses.
Side Effect — difference?
Related to pharmacology; can be beneficial, neutral, or harmful.
ADE — definition?
Adverse outcome post-drug use; includes all ADRs.
Type A ADR — characteristics?
Predictable, dose-dependent, common, preventable.
Type B ADR — characteristics?
Unpredictable, not dose-dependent, often serious.
Factors influencing susceptibility?
Age, gender, genetics, co-morbidities, polypharmacy.
Immunological reactions — example?
Allergic reactions like rashes, anaphylaxis.
Answer 10 questions on Understanding Adverse Drug Reactions and Susceptibility.
1. What is an adverse drug reaction (ADR)?
2. What is the primary role of understanding the pharmacological mechanisms and factors influencing individual susceptibility in adverse drug reactions?
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